Presse médicale
Il y a 1 mois
Changes of stress proteins and oxidative stress indices with progressive exercise training in elderly men

Publication date: Available online 17 March 2017
Source:Science & Sports
Author(s): S. Atashak, K. Azizbeigi, M. Ali Azarbayjani, S.R. Stannard, F. Dehghan, R. Soori
PurposeExcessive generation of free radicals and oxidative stress play an important role in acceleration of the aging process and contribute many chronic diseases. Nevertheless, it has been shown that the elderly who are physically active benefit from exercise-induced adaptation in cellular antioxidant defense systems and associated increase in the generation heat shocks proteins (HSPs). Therefore, the aim of the present research was to investigate the effects of 14 weeks participation in concurrent (resistance and aerobic) training on indices of oxidative stress and HSP70 concentration in inactive elderly men.MethodsTwenty-four inactive elderly men voluntarily participated in this research and were assigned to either training (n=12) or control (n=12) groups. In the control group, participants were advised to maintain their normal lifestyle during the study, while the training group was prescribed a combination of resistance and aerobic training for 14 weeks. At baseline and after 14 weeks, venous blood samples were obtained for measurement of malondialdehyde (MDA) and carbonyl protein (PC), total antioxidant capacity (TAC) and HSP70 concentration.ResultsThe results indicate very significant effects of exercise training on all measured experimental variables when compared to the control group: MDA and PC concentrations decreasing, whilst HSP70 and TAC in aged men were increased significantly after exercise training in training g[...]

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Presse médicale
Il y a 1 heures
ScienceDirect

Publication date: Available online 22 April 2017
Source:Morphologie
Author(s): J. Mao, Y. Wang, E. Philippe, T. Cianciulli, I. Vesely, D. How, J.-M. Bourget, L. Germain, Z. Zhang, R. Guidoin
IntroductionCross-linking and anti-calcification of prosthetic heart valves have been continuously improved to prevent degeneration and calcification. However, non-calcific structural deteriorations such as cuspal dehiscences along the stent still require further analysis.Material and methodBased upon the previous analysis of an explanted valve after 7 years, a fresh commercial aortic valve was embedded in poly(methyl methacrylate) (PMMA) and cut into slices to ensure the detailed observation of the assembly and material structures. A pericardial patch embossed to provide the adequate shape of the cusps was investigated after paraffin embedding and appropriate staining. The microstructural damages that occurred during manufacturing process were identified and evaluated by light microscopy, polarized microscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM).ResultsThe wavy collagen bundles, the key structure of the pericardium patch, were damaged to a great extent at suture sites along the stent and in the compressed areas around the stent post. The fixation of the embossed pericardium patch along the plots of the stent aggravated the microstructural modifications. The damages mainly appeared as the elimination of collagen bundle waviness and delamination between the bundles.ConclusionConsidering [...]

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Amazon medecine
Le meilleur médicament, c'est vous !
Frédéric Saldmann
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Guy Thomas
Il y a 3 heures
What\'s Up Doc - Toute l\'actualité

Guy Thomas est PU-PH en psychiatrie à l’hôpital Saint-Antoine et directeur adjoint de l'unité Inserm-UPMC 1136.

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News Santé | Actualités & informations - Yahoo Actualités FR

Ah l'humilité... Je croyais en être bourrée... Et pourtant je perçois déjà mes limites. Ou comment j'ai du mal a raconter, que bientôt, j'exercerai un job peu valorisé. Pas facile. Pas facile de sortir de mes représentations sociales bien encrées et d'assumer. Oui après avoir été cadre dans une société, je vais exercer le métier d'aide a domicile... L'écart est grand, professionnellement parlant... Mais je ne compte pas laisser le regard des autres me faire changer d'[...]

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Amazon medecine
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Frédéric Saldmann
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APF ICM

Bibliographie : Parents handis, pas à pas, du désir d'enfant à son entrée en maternelle.

2e édition, janvier 2017, 52 pages.

Le blog : http://parentsh.blogs.apf.asso.fr.